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Tissue-Engineered Cervix

Mayer-Rokitansky-Küster-Hauser syndrome, or MRKH, is a rare disease affecting approximately 1 of every 5000 women. It can be characterized by a very shortened vaginal canal or no vagina at all. Surgeons, particularly Prof. Dr. Sara Brucker and her team at the University Women's Hospital Tübingen, have designed a surgical procedure to (re)create a neovagina for MRKH patients, which enables the patients to have normal sexual lives, yet they are still unable to bear children due to the absence of a cervix. It is our goal to engineer an implantable cervix, so these women may one day carry a baby to term.

>MRKH Genetics

University Women's Hospital Tübingen, under the direction of Prof. Dr. Diethelm Wallwiener, is one of the premier women's hospitals in Europe, which hosts the Treatment and Research Centre for Rare Diseases. Within this center, our group is working closely with the Institute of Medical Genetics and Applied Genomics and the surgical department to discover the genetic mechanisms involved in rare diseases such as MRKH.

Endometriosis

We are working closely with the Women's Hospital medical department to find new non-invasive methods to diagnose very early stages of endometriosis. It is our goal to create a new gold standard for endometriosis detection, which may lead to new processes to manage the disease.

Cardiovascular Disease

Women's cardiovascular disease has not been of great focus over the past decades. Despite their physical differences, women are typically treated in the same manner as men. While this has been the norm, it is now becoming more apparent that science must spend more time investigating women specific issues in cardiovascular disease and prevention.